This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.
|Author||Daniel Pique, John Greally, Jessica Mar|
|Bioconductor views||GeneExpression Sequencing|
|Maintainer||Daniel Pique <[email protected]>|
|Package repository||View on Bioconductor|
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