oncomix: Identifying Genes Overexpressed in Subsets of Tumors from Tumor-Normal mRNA Expression Data

This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.

Package details

AuthorDaniel Pique, John Greally, Jessica Mar
Bioconductor views GeneExpression Sequencing
MaintainerDaniel Pique <[email protected]>
Package repositoryView on Bioconductor
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oncomix documentation built on Oct. 31, 2019, 6:18 a.m.