progeny: Pathway RespOnsive GENes for activity inference from gene expression

This package provides a function to infer pathway activity from gene expression using PROGENy. It contains the linear model we inferred in the publication "Perturbation-response genes reveal signaling footprints in cancer gene expression".

README.md Applying PROGENy on single-cell RNA-seq data PROGENy pathway signatures: Application to Bulk transcriptomics

Vignettes Man pages API and functions Files

Package details
Author	Michael Schubert [aut], Alberto Valdeolivas [cre, ctb] (<https://orcid.org/0000-0001-5482-9023>), Christian H. Holland [ctb] (<https://orcid.org/0000-0002-3060-5786>), Igor Bulanov [ctb], Aurélien Dugourd [ctb]
Bioconductor views	FunctionalPrediction GeneExpression GeneRegulation SystemsBiology
Maintainer	Alberto Valdeolivas <alvaldeolivas@gmail.com>
License	Apache License (== 2.0) \| file LICENSE
Version	1.12.0
URL	https://github.com/saezlab/progeny
Package repository	View on Bioconductor
Installation	Install the latest version of this package by entering the following in R: `if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("progeny")`