roar-package: Identify differential APA usage from RNA-seq alignments
In roar: Identify differential APA usage from RNA-seq alignments
Description
Identify preferential usage of APA sites,
comparing two biological conditions, starting from known alternative sites and
alignments obtained from standard RNA-seq experiments.
Details
The codeRoarDataset class exposes methods to perform the whole analysis, in order to
identify genes with preferential expression of long/short isoforms in a condition with respect to
another one. The needed input data are alignments deriving from RNA-seq experiments of the
two conditions and a set of coordinates of APA sites for genes with an alternative APA site
proximal to the one used “normally”.
Author(s)
Elena Grassi <grassi.e@gmail.com>
roar documentation built on Nov. 8, 2020, 4:50 p.m.
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Description
Identify preferential usage of APA sites, comparing two biological conditions, starting from known alternative sites and alignments obtained from standard RNA-seq experiments.
Details
The codeRoarDataset class exposes methods to perform the whole analysis, in order to identify genes with preferential expression of long/short isoforms in a condition with respect to another one. The needed input data are alignments deriving from RNA-seq experiments of the two conditions and a set of coordinates of APA sites for genes with an alternative APA site proximal to the one used “normally”.
Author(s)
Elena Grassi <grassi.e@gmail.com>
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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