safe: Significance Analysis of Function and Expression

SAFE is a resampling-based method for testing functional categories in gene expression experiments. SAFE can be applied to 2-sample and multi-class comparisons, or simple linear regressions. Other experimental designs can also be accommodated through user-defined functions.

Package details

AuthorWilliam T. Barry
Bioconductor views DifferentialExpression GeneSetEnrichment Pathways Software StatisticalMethod
MaintainerLudwig Geistlinger <>
LicenseGPL (>= 2)
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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safe documentation built on Nov. 8, 2020, 5:37 p.m.