sigsquared: Gene signature generation for functionally validated signaling pathways

By leveraging statistical properties (log-rank test for survival) of patient cohorts defined by binary thresholds, poor-prognosis patients are identified by the sigsquared package via optimization over a cost function reducing type I and II error.

Getting started

Package details

AuthorUnJin Lee
MaintainerUnJin Lee <>
LicenseGPL version 3
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


Try the sigsquared package in your browser

Any scripts or data that you put into this service are public.

sigsquared documentation built on Nov. 8, 2020, 6:59 p.m.