OneArm.CondPower: Conditional power for one-arm, two-stage design with two...

In ADCT: Adaptive Design in Clinical Trials

Description

Given the group sequential design information, returns the conditional power.

Usage

OneArm.CondPower(mu1, mu2, n1, n2, rho, tau, alpha2, alternative)

Arguments

mu1	mean value for the first stage (endpoint 1).
mu2	mean value for the second stage (endpoint 2).
n1	sample size for the first stage.
n2	sample size for the second stage.
rho	correlation coefficient between two coprimary endpoints.
tau	information time for the interim analysis.
alpha2	significant level for the second stage.
alternative	indicates the alternative hypothesis and must be one of "two.sided" or "two.sided".

Value

The evaluated power with attributes and computational error.

Author(s)

Yalin Zhu

References

Chang, M. (2014). Adaptive design theory and implementation using SAS and R. CRC Press.

Examples

# Example in Chang (2014) page  277
OneArm.CondPower(mu1=0.1333, mu2=0.1605, n1=130, n2=130, rho=0.35,
 tau=0.5, alpha2=0.024, alternative = "one.sided")
OneArm.CondPower(mu1=0.1333, mu2=0.1605, n1=130, n2=414, rho=0.35,
 tau=0.5, alpha2=0.024, alternative = "one.sided")

ADCT documentation built on May 2, 2019, 9:40 a.m.