AGSDest: Estimation in Adaptive Group Sequential Trials

Calculation of repeated confidence intervals as well as confidence intervals based on the stage-wise ordering in group sequential designs and adaptive group sequential designs. For adaptive group sequential designs the confidence intervals are based on the conditional rejection probability principle. Currently the procedures do not support the use of futility boundaries or more than one adaptive interim analysis.

Package details

AuthorNiklas Hack [aut, cre], Werner Brannath [aut], Matthias Brueckner [aut]
MaintainerMatthias Brueckner <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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AGSDest documentation built on May 2, 2019, 9:13 a.m.