type I error rate of a GSD

Description

typeIerr is a function that computes the type I error rate of a GSD.

Usage

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typeIerr(GSD)

Arguments

GSD

object of the class GSTobj or list with the following elements: K = number of stages, a = vector with futility boundaries (not supported yet), b = rejection boundaries, t = vector with information fractions; see example blow.

Value

typeIerr returns the type I error rate of a GSD.

Author(s)

Niklas Hack niklas.hack@meduniwien.ac.at and Werner Brannath werner.brannath@meduniwien.ac.at

References

O'Brien, PC, Fleming, TR (1979) ”A multiple testing procedure for clinical trials”, Biometrics, 35 , 549-556

Schoenfeld, D (2001) ”A simple Algorithm for Designing Group Sequential Clinical Trials”, Biometrics, 27, 972-974

See Also

GSTobj

Examples

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##The following calculates the type I error rate of a GSD.

GSD <- list(K=4,a=rep(-8,4),b=c(4.333,2.963,2.359,2.014),
t=c(0.25,0.5,0.75,1),Imax=0.22)

typeIerr(GSD)