localPP: Local Power Prior for Bayesian Basket Trial

In BasketTrial: Bayesian Basket Trial Design and Analysis

Local Power Prior for Bayesian Basket Trial

Description

Local Power Prior for Bayesian Basket Trial

Usage

localPP(
  nDat,
  yDat,
  be.a0 = NULL,
  be.b0 = NULL,
  a = 1,
  delta = 0.4,
  method = "PEB",
  symmetry = FALSE
)

Arguments

nDat	a vector of length B for the sample size in each basket.
yDat	a vector of length B for the number of responses in each basket.
be.a0	a vector of length B for beta prior parameter a0 in each basket.
be.b0	a vector of length B for beta prior parameter b0 in each basket.
a	the global control parameter in the local PP 3-component framework.
delta	the threshold parameter in the local PP 3-component framework.
method	either PEB for the pairwise empirical Bayes or GEB for the global empirical Bayes.
symmetry	logical variable to indicate whether the similarity matrix will be set to be symmetric; default is FALSE.

Value

It returns a list including the posterior beta parameters and similarity matrix.

References

Zhou, H., Shen, R., Wu, S., & He, P. (2023). A Bayesian Basket Trial Design Using Local Power Prior. arXiv preprint arXiv:2312.15352.

Examples

localPP(nDat = c(25, 25, 25, 25, 25), yDat = c(2,9,11,13,20),
be.a0 = rep(0.5, 5), be.b0 = rep(0.5, 5), a = 4, delta = 1, method = "PEB")

BasketTrial documentation built on June 18, 2025, 5:08 p.m.