This data set contains data from a MLPA assay for a case-control study. The data has intensities for two genes that can be used to infer copy number status. It also contains the TRUE copy number status obtained by using PCR technology.
dataMLPA is a data.frame with the following columns:
|id||The unique identifiers of individuals|
|casco||Case-control stauts 0:control 1:case|
|Gene1||Intensities for Gene1|
|Gene2||Intensities for Gene2|
|PCR.Gene1||True copy number status for Gene1|
|PCR.Gene2||True copy number status for Gene2|
|quanti||Simulated continuos variable. It was generated to illustrate how to perform association analysis between a CNV and continuous traits|
|cov||Simulated continuous variable. It was generated to illustrate how to perform association adjusting for covariates|
This data set was generated and kindly provided by Estivill's lab. The data is still unpublished and it has been made available in a blinded format for reproducing the findings presented in the paper
Gonzalez JR, Subirana I, Escaramis G, Peraza S, Caceres A, Estivill X and Armengol L. Accounting for uncertainty when assessing association between copy number and disease: a latent class model. BMC Bioinformatics, 2009;10:172.
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