Description Usage Arguments Details Value Author(s) References Examples
Those genes not significantly more variable than the median gene are filtered out.
1 | varianceBasedfilter(exprs,p)
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exprs |
a data frame or matrix with rows for variables (genes) and columns for samples. |
p |
the probability cut-off of the chi-squared model of the gene-specific variance-like statistics. |
This is an approximate test of the hypothesis that gene has the same variance as the median variance. A statistical significance criterion based on the variance can be used. If the significance criterion is chosen, then the variance of the log-values for each gene is compared to the median of all the variances. The quantity for each gene compared to a percentile of the chi-square distribution with n-1 degrees of freedom. Those genes not significantly more variable than the median gene are filtered out [BRB-ArrayTools Version 3.7].
A data frame or matrix with a reduced number of rows.
Jing Yang
Dr. Richard Simon & Amy Peng Lam, BRB-ArrayTools (v3.7) User's Manual: 'Log expression variation filter'.
1 2 | data(exprs1)
varianceBasedfilter(exprs1,0.05)
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