INMB: A Reference Class to represent the INMB (Incremental Net...

In EBASS: Sample Size Calculation Method for Cost-Effectiveness Studies Based on Expected Value of Perfect Information

Description

The net monetary benefit (NMB) of an intervention is given by E x Lambda - C, where E and C are the effectiveness and cost of this intervention, and Lambda is the threshold value for a unit of effectiveness, the ceiling incremental cost-effectiveness ratio. When the NMB is positive, the value of the intervention's effectiveness overpasses its cost. When evaluating the cost-effectiveness of a new intervention in comparison with the reference, one can estimate the difference between the net monetary benefit of the new or experimental intervention (NMBn) and the net monetary benefit of the reference (NMBr). This difference is known as the incremental net monetary benefit (INMB), which is given by: INMB = NMBn - NMBr = de x lambda - dc. The new intervention is cost-effective if INMB is positive.

Fields

de

: Expected point estimate of the difference in mean effectiveness (effectiveness in the experimental group minus effectiveness in the reference group)

dc

: Expected point estimate of the difference in mean cost (cost in the experimental group minus cost in the reference group)

object_lambda

: object containing the ceiling cost-effectiveness ratio or maximum acceptable cost of a unit of effectiveness. See create_object_lambda

Methods

get_inmb():

Returns the calculated Incremental Net Monetary Benefit (inmb)

set_dc(dc):

sets the dc of this INMB object

set_de(de):

sets the de of this INMB object

set_object_lambda(object_lambda):

sets the object_lambda of this INMB object

See Also

INMB_DIRECT the parent class

create_object_inmb the constructor

Examples

## First, create a lambda object
object_lambda <- create_object_lambda (20000)
## Then, create an inmb object
object_inmb <- create_object_inmb(de = 0.04, dc=-168, object_lambda = object_lambda)
## inmb is calculated by methods inside the object. Retrieve the inmb :
object_inmb$get_inmb()

Example output

[1] 968

EBASS documentation built on May 1, 2019, 6:54 p.m.