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Implements Escalation With Overdose Control trial designs using two drug combinations described by this paper <doi:10.1002/sim.6961>(Tighiouart et al., 2016). It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.
Package details |
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Author | Yujie Cui [aut, cre], Quanlin Li [aut], Mourad Tighiouart [aut] |
Maintainer | Yujie Cui <yujie.cui@cshs.org> |
License | GPL (>= 2) |
Version | 1.0 |
Package repository | View on CRAN |
Installation |
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