FREGAT-package: FREGAT: Family REGional Association Tests
In FREGAT: Family REGional Association Tests
Description
Details
Author(s)
References
Description
The FREGAT package supplies the most common and efficient
tests for the region-based association analysis aimed at identification
of rare genetic variants for family-based, genetically related
or population samples. Tests implemented are FFBSKAT (fast family-based
sequence kernel association test), FFBSKAT optimal, famBT (family burden
test), famFLM (family functional linear model, a functional data analysis
approach), and MLR (standard multiple linear regression). The methods
provide regional association testing of a set of SNPs with a continuous
phenotype in the presence of additional covariates and within-family
correlations.
Details
Package: FREGAT
Type: Package
License: GPLv3
Author(s)
Nadezhda Belonogova <belon@bionet.nsc.ru>
Gulnara Svishcheva <gulsvi@mail.ru>
The authors are very grateful to Dr. Anatoly Kirichenko for technical support
and Prof. Tatiana Axenovich for scientific guidance.
References
Belonogova N.M., Svishcheva G.R., Axenovich T.I. (2016) FREGAT: an R package for region-based association analysis. Bioinformatics, V32(15), P. 2392-2393.
FREGAT documentation built on Jan. 15, 2018, 9:04 a.m.
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Description Details Author(s) References
Description
The FREGAT package supplies the most common and efficient tests for the region-based association analysis aimed at identification of rare genetic variants for family-based, genetically related or population samples. Tests implemented are FFBSKAT (fast family-based sequence kernel association test), FFBSKAT optimal, famBT (family burden test), famFLM (family functional linear model, a functional data analysis approach), and MLR (standard multiple linear regression). The methods provide regional association testing of a set of SNPs with a continuous phenotype in the presence of additional covariates and within-family correlations.
Details
Package: FREGAT
Type: Package
License: GPLv3
Author(s)
Nadezhda Belonogova <belon@bionet.nsc.ru>
Gulnara Svishcheva <gulsvi@mail.ru>
The authors are very grateful to Dr. Anatoly Kirichenko for technical support
and Prof. Tatiana Axenovich for scientific guidance.
References
Belonogova N.M., Svishcheva G.R., Axenovich T.I. (2016) FREGAT: an R package for region-based association analysis. Bioinformatics, V32(15), P. 2392-2393.
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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