return.tte.int.data.req: Title

In GNGTools: Tools for Go/No-Go Decision-Making Framework

Title

Description

Title

Usage

return.tte.int.data.req(
  m.con.prior = 0.001,
  m.trt.prior = 0.001,
  HR.prior = 1,
  ARatio = 1,
  interim.HR = c(0.8, 0.7, 0.65, 0.68, 0.7),
  interim.m = c(100, 200, 300, 400, 750),
  final.m = 1000,
  HR.tv = 0.7,
  HR.lrv = 0.9,
  tau.tv = 0.1,
  tau.lrv = 0.8,
  tau.ng = 0.65,
  HR.ng = NULL,
  HR.go = NULL,
  go.thresh = 0.8,
  ng.thresh = 0.8,
  include_nogo = TRUE
)

Arguments

m.con.prior	prior number of control events
m.trt.prior	prior number of treatment events
HR.prior	prior estimate for HR
ARatio	randomization ratio
interim.HR	Interim HR
interim.m	Interim events
final.m	final events
HR.tv	TPP Target Value aka Base TPP
HR.lrv	TPP Lower Reference Value aka Max TPP (large HRs lead to No-Go)
tau.tv	threshold associated with Base TPP
tau.lrv	threshold associated with Min TPP
tau.ng	threshold associated with No-Go
HR.ng	HR needed for ng; leave null for standard rule
HR.go	HR needed for go; leave null for standard rule
go.thresh	go threshold for predictive probability
ng.thresh	no-go threshold for predictive probability
include_nogo	logical

Value

A data.frame is returned

Examples

holdit <- return.tte.int.data.req()
head(holdit)

GNGTools documentation built on Dec. 16, 2022, 5:09 p.m.