| grin.results | R Documentation |
A precomputed GRIN2 results object generated from the example genomic lesion
dataset included with the package. The object represents a standard
gene-level GRIN2 analysis and is provided for use in examples of downstream
analysis, visualization, and export functions without repeatedly running
grin.stats().
A named list containing the following 10 components:
gene.hitsA data frame containing the primary GRIN2 analysis results for each gene, including lesion counts, affected-subject counts, lesion-specific probabilities, p-values, q-values, and constellation test statistics.
lsn.dataThe genomic lesion dataset used as input to grin.stats.
Each row corresponds to a genomic lesion together with its genomic
coordinates, lesion type, and subject identifier.
gene.dataThe gene annotation data used during the analysis, including genomic coordinates and gene identifiers.
gene.lsn.dataA data frame describing overlaps between genomic lesions and genes.
chr.sizeChromosome target sizes used for probability calculations.
gene.indexInternal index used to efficiently identify chromosome-specific groups of genes during the analysis.
lsn.indexInternal index used to efficiently identify chromosome-specific groups of genomic lesions during the analysis.
gene.exon.sizeGene-specific exon target sizes used for exon-level analyses.
This component is NULL for the standard gene-level example.
exon.chrom.sizeChromosome exon target sizes used for exon-level analyses.
This component is NULL for the standard gene-level example.
exon_levelIndicates which lesion types were modeled using exon-level target sizes.
This component is NULL for the standard gene-level example.
The object was generated using:
grin.results <- grin.stats( lsn.data = lesion_data, gene.data = hg38_gene_annotation, chr.size = hg38_chrom_size )
This dataset is intended primarily for package examples and demonstrations.
It allows downstream GRIN2 functions to be illustrated without repeatedly
running grin.stats. The object contains the complete output
returned by grin.stats and can therefore be supplied directly
to functions that require a GRIN2 results object.
Generated from the example datasets
lesion_data, hg38_gene_annotation, and
hg38_chrom_size included with the GRIN2 package.
grin.stats,
lsn.transcripts.plot,
grin.oncoprint.mtx,
write.grin.xlsx
data("grin.results")
# Display the available components.
names(grin.results)
# View the first few rows of the primary results table.
head(grin.results$gene.hits)
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