GWAF-package: Genome-wide association/interaction analysis and rare variant...

Description Details Author(s)


For continuous traits, GWAF package provides two sets of functions for each of genome-wide association/interaction analyses with observed/imputed SNP genotypes for family data. One fits Linear Mixed Effects (LME) model and the other fits Generalized Estimation Equation (GEE) model to accounting for within pedigree correlation. While for dichotomous trait, GWAF package provides functions to fit GEE model for genome-wide association/interaction analyses. For rare variant analysis, GWAF fits LME and generalized linear mixed effects (GLMM) model for continuous traits and dichotomous traits, respectively. In addition, GWAF package also provides functions for making genome-wide p-values plot and QQ plot that contains genomic control parameter estimate and generating scripts for genome-wide association analysis. Please read UsingGWAF.pdf for more information including examples and description to output files.


Package: GWAF
Type: Package
Version: 2.1
Date: 2013-06-06
License: GPL (>= 2)


Qiong Yang <> and Ming-Huei Chen <>

Maintainer: Ming-Huei Chen <>

GWAF documentation built on May 2, 2019, 2:47 p.m.