GWAF-package: Genome-wide association/interaction analysis and rare variant...
In GWAF: Genome-Wide Association/Interaction Analysis and Rare Variant Analysis with Family Data
Description
For continuous traits, GWAF package provides two sets of functions for each of genome-wide association/interaction analyses
with observed/imputed SNP genotypes for family data. One fits Linear Mixed Effects (LME) model and the other fits Generalized Estimation Equation (GEE) model
to accounting for within pedigree correlation. While for dichotomous trait, GWAF package provides functions to fit GEE model for
genome-wide association/interaction analyses. For rare variant analysis, GWAF fits LME and generalized linear mixed effects (GLMM) model
for continuous traits and dichotomous traits, respectively. In addition, GWAF package
also provides functions for making genome-wide p-values plot and QQ plot that contains genomic control
parameter estimate and generating scripts for genome-wide association analysis.
Please read UsingGWAF.pdf for more information including examples and description to output files.
Details
Package: GWAF
Type: Package
Version: 2.1
Date: 2013-06-06
License: GPL (>= 2)
Author(s)
Qiong Yang <qyang@bu.edu> and Ming-Huei Chen <mhchen@bu.edu>
Maintainer: Ming-Huei Chen <mhchen@bu.edu>
GWAF documentation built on May 2, 2019, 2:47 p.m.
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Description
For continuous traits, GWAF package provides two sets of functions for each of genome-wide association/interaction analyses
with observed/imputed SNP genotypes for family data. One fits Linear Mixed Effects (LME) model and the other fits Generalized Estimation Equation (GEE) model
to accounting for within pedigree correlation. While for dichotomous trait, GWAF package provides functions to fit GEE model for
genome-wide association/interaction analyses. For rare variant analysis, GWAF fits LME and generalized linear mixed effects (GLMM) model
for continuous traits and dichotomous traits, respectively. In addition, GWAF package
also provides functions for making genome-wide p-values plot and QQ plot that contains genomic control
parameter estimate and generating scripts for genome-wide association analysis.
Please read UsingGWAF.pdf for more information including examples and description to output files.
Details
| Package: | GWAF |
| Type: | Package |
| Version: | 2.1 |
| Date: | 2013-06-06 |
| License: | GPL (>= 2) |
Author(s)
Qiong Yang <qyang@bu.edu> and Ming-Huei Chen <mhchen@bu.edu>
Maintainer: Ming-Huei Chen <mhchen@bu.edu>
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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