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GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests
The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
Getting started
Browse package contents
Package details |
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| Author | ChangJiang Xu and Celia M.T. Greenwood |
| Maintainer | ChangJiang Xu <changjiang.h.xu@gmail.com> |
| License | GPL (>= 2) |
| Version | 1.2 |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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