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The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
Package details |
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Author | ChangJiang Xu and Celia M.T. Greenwood |
Maintainer | ChangJiang Xu <changjiang.h.xu@gmail.com> |
License | GPL (>= 2) |
Version | 1.2 |
Package repository | View on CRAN |
Installation |
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