GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests

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The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Author
ChangJiang Xu and Celia M.T. Greenwood
Date of publication
2016-09-12 20:55:00
Maintainer
ChangJiang Xu <changjiang.h.xu@gmail.com>
License
GPL (>= 2)
Version
1.2

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Man pages

GWsignif
Estimating Genome-Wide Significance for Whole Genome...
GWsignif-package
Estimating Genome-Wide Significance for Whole Genome...

Files in this package

GWsignif
GWsignif/NAMESPACE
GWsignif/R
GWsignif/R/GWsignif.R
GWsignif/MD5
GWsignif/DESCRIPTION
GWsignif/man
GWsignif/man/GWsignif-package.Rd
GWsignif/man/GWsignif.Rd