GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Package details

AuthorChangJiang Xu and Celia M.T. Greenwood
MaintainerChangJiang Xu <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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GWsignif documentation built on May 2, 2019, 11:27 a.m.