The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
|Author||ChangJiang Xu and Celia M.T. Greenwood|
|Date of publication||2016-09-12 20:55:00|
|Maintainer||ChangJiang Xu <firstname.lastname@example.org>|
|License||GPL (>= 2)|