GWsignif-package: Estimating Genome-Wide Significance for Whole Genome...

Description Details Author(s) References

Description

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Details

Package: GWsignif
Type: Package
Version: 1.2
Date: 2016-09-10
License: GLP 2.0 or greater

Author(s)

ChangJiang Xu and Celia M.T. Greenwood Maintainer: ChangJiang Xu <changjiang.h.xu@gmail.com>

References

ChangJiang Xu, Ioanna Tachmazidou, Klaudia Walter, Antonio Ciampi, Eleftheria Zeggini, Celia M.T. Greenwood (2014) Estimating genome-wide significance for whole genome sequencing studies. Genetic Epidemiology


GWsignif documentation built on May 2, 2019, 11:27 a.m.