Description Details Author(s) References
The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
Package: | GWsignif |
Type: | Package |
Version: | 1.2 |
Date: | 2016-09-10 |
License: | GLP 2.0 or greater |
ChangJiang Xu and Celia M.T. Greenwood Maintainer: ChangJiang Xu <changjiang.h.xu@gmail.com>
ChangJiang Xu, Ioanna Tachmazidou, Klaudia Walter, Antonio Ciampi, Eleftheria Zeggini, Celia M.T. Greenwood (2014) Estimating genome-wide significance for whole genome sequencing studies. Genetic Epidemiology
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