HeritSeq: Heritability of Gene Expression for Next-Generation Sequencing

Statistical framework to analyze heritability of gene expression based on next-generation sequencing data and simulating sequencing reads. Variance partition coefficients (VPC) are computed using linear mixed effects and generalized linear mixed effects models. Compound Poisson and negative binomial models are included. Reference: Rudra, Pratyaydipta, et al. "Model based heritability scores for high-throughput sequencing data." BMC bioinformatics 18.1 (2017): 143.

Getting started

Package details

AuthorW. Jenny Shi [aut, cre], Pamela Russell [aut], Pratyaydipta Rudra [aut, cre], Brian Vestal [aut, cre], Katerina Kechris [aut], Laura Saba [aut]
MaintainerW. Jenny Shi <wjennyshi@gmail.com>
LicenseGPL-2
Version1.0.1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("HeritSeq")

Try the HeritSeq package in your browser

Any scripts or data that you put into this service are public.

HeritSeq documentation built on May 1, 2019, 10:19 p.m.