meta_analysis: Meta-analysis for KnockoffTrio

In KnockoffTrio: GWAS with Trio and Duo Data using Knockoff Statistics for FDR Control

Meta-analysis for KnockoffTrio

Description

Meta-analysis for KnockoffTrio

Usage

meta_analysis(window, n = NA, M = 10)

Arguments

window	A list of windows for the analysis results from different cohorts/studies.
n	A positive integer vector for the number of families in each cohort/study. For weighted meta-analysis, a study's weight is based on the number of families. The default is NA for unweighted meta-analysis.
M	A positive integer for the number of knockoffs. The default is 10.

Value

A data frame for the meta-analysis results.

Examples

data(KnockoffTrio.example)
knockoff<-create_knockoff(trio.hap=KnockoffTrio.example$trio.hap,
          duo.hap=KnockoffTrio.example$duo.hap, pos=KnockoffTrio.example$pos, M=10)
window<-KnockoffTrio(trio=KnockoffTrio.example$trio, trio.ko=knockoff$trio.ko,
        duo=knockoff$duo, duo.ko=knockoff$duo.ko, pos=KnockoffTrio.example$pos)
window.list<-list(window,window)
window.meta<-meta_analysis(window.list,M=10)
result<-causal_loci(window.meta,M=10,fdr=0.1)

KnockoffTrio documentation built on April 4, 2025, 2:14 a.m.