Latent Class Analysis of phenotypic measurements in pedigrees and model selection based on one of two methods: likelihood-based cross-validation and Bayesian Information Criterion. Computation of individual and triplet child-parents weights in a pedigree is performed using an upward-downward algorithm. The model takes into account the familial dependence defined by the pedigree structure by considering that a class of a child depends on his parents classes via triplet-transition probabilities of the classes. The package handles the case where measurements are available on all subjects and the case where measurements are available only on symptomatic (i.e. affected) subjects. Distributions for discrete (or ordinal) and continuous data are currently implemented. The package can deal with missing data.
|Author||Arafat TAYEB <firstname.lastname@example.org>, Alexandre BUREAU <email@example.com> and Aurelie Labbe <firstname.lastname@example.org>|
|Maintainer||Alexandre BUREAU <email@example.com>|
|Package repository||View on CRAN|
Install the latest version of this package by entering the following in R:
Any scripts or data that you put into this service are public.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.