alog_pcfb | R Documentation |
A dataset from a systematic review of Randomised-Controlled Trials (RCTs) comparing different doses of alogliptin with placebo \insertCitelangford2016MBNMAtime. The systematic review was simply performed and was intended to provide data to illustrate a statistical methodology rather than for clinical inference. Alogliptin is a treatment aimed at reducing blood glucose concentration in type II diabetes. The outcome is continuous, and aggregate data responses correspond to the mean change in HbA1c from baseline to follow-up. The dataset includes 14 Randomised-Controlled Trials (RCTs), comparing 5 different doses of alogliptin with placebo, leading to 6 different treatments (combination of dose and agent) within the network.
alog_pcfb
A data frame in long format (one row per arm and study), with 46 rows and 9 variables:
studyID
Study identifiers
clinicaltrialGov_ID
The clinicaltrial.gov ID code
agent
Character data indicating the agent to which participants were randomised
dose
Numeric data indicating the standardised dose received
treatment
Character data indicating the treatment (combination of agent and dose) to which participants were randomised
time
Numeric data indicating the time at which the observation was measured (given in weeks)
y
Numeric data indicating the mean change from baseline in blood glucose concentration (mg/dL) in a study arm
se
Numeric data indicating the standard error for the mean change from baseline in blood glucose concentration (mg/dL) in a study arm
n
Numeric data indicating the number in each arm at each follow-up time
alog_pcfb
is a data frame in long format (one row per observation, arm and study),
with the variables studyID
, clinicaltrialGov_ID
, agent
, dose
, treatment
, time
, y
, se
, and n
.
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