R/statin101.R

In MDDC: Modified Detecting Deviating Cells Algorithm in Pharmacovigilance

#' FDA statin dataset with 101 adverse events
#'
#' @description A 102 by 5 data matrix of a contingency table processed from
#' the FDA Adverse Event Reporting System (FAERS) database from Q1 2021 to
#' Q4 2023.
#'
#' @format A data matrix with 102 rows and 5 columns.
#'
#' @details A 102 by data matrix of a contingency table from the FDA Adverse
#' Event Reporting System (FAERS) database, covering Q1 2021 to Q4 2023.
#'
#' The 101 rows correspond to the AEs with the highest overall
#' frequency (row marginals) reported during the period. The reported AEs -
#' "Off label use" and "Drug ineffective" have been excluded.
#'
#' The 5 columns include 4 statin medications and an "other" column.
#' Marginal totals for each drug: 101,462 for Atorvastatin, 9,203 for
#' Fluvastatin, 130,994 for Rosuvastatin,
#' 87,841 for Simvastatin, and 57,393,834 for Other drugs.
#'
#' Also refer to supplementary material of:
#'
#'  Ding, Y., Markatou, M., & Ball, R. (2020). An evaluation of statistical
#'  approaches to postmarketing surveillance. Statistics in Medicine, 39(7),
#'  845-874
#'
#'  for the data generation process.
#'  The quarterly files can be found in
#'  \url{https://fis.fda.gov/extensions/FPD-QDE-FAERS/FPD-QDE-FAERS.html}.
#'
#' @examples
#' data(statin101)
#' head(statin101)
#'
"statin101"