Rats: Teratology study

In MLGdata: Datasets for Use with Salvan, Sartori and Pace (2020)

Description

Teratology experiment investigating effects of dietary regimens or chemical agents on the fetal development of rats in a laboratory setting. The experiment, as describred in Agresti (2015, Section 8.2.4), regards female rats on iron-deficient diets, assigned to four groups. Rats in group 1 were given placebo injections, and rats in other groups were given injections of an iron supplement. This was done on days 7 and 10 in group 2, on days 0 and 7 in group 3, and weekly in group 4. The 58 rats were made pregnant, sacrificed after 3 weeks, and then the total number of dead fetuses was counted in each litter, as was the mother’s hemoglobin level.

Usage

Rats

Format

A data frame with 58 observations on the following 5 variables

litter

litter index

group

group index (1, ..., 4)

h

hemoglobin level of the mother

n

number of fetuses in the litter

s

number of dead fetuses in the litter

Source

Agresti, A. (2015). Foundations of Linear and Generalized Linear Models. Hoboken: Wiley.

Package catdata

References

Moore, D.F. and Tsiatis, A. (1991). Robust estimation of the variance in moment methods for extra-binomial and extra-Poisson variation. Biometrics, 47, 383-401.

MLGdata documentation built on Oct. 23, 2020, 7:47 p.m.