ACF: Aberrant Crypt Foci in Rat Colons

ACFR Documentation

Aberrant Crypt Foci in Rat Colons

Description

Numbers of aberrant crypt foci (ACF) in colons of 66 rats subjected to a various numbers of dose of the carcinogen azoxymethane (AOM), sacrificed at 3 different times.

Usage

ACF

Format

This data frame contains the following columns:

INJ

The number of carcinogen injections

T

Time of sacrifice, in weeks following injection of AOM

COUNT

The number of ACF observed in each rat colon

Source

Ranjana P. Bird, Faculty of Human Ecology, University of Manitoba, Winnipeg, Canada.

References

E.A. McLellan, A. Medline and R.P. Bird. Dose response and proliferative characteristics of aberrant crypt foci: putative preneoplastic lesions in rat colon. Carcinogenesis, 12(11): 2093-2098, 1991.

Examples

sapply(split(ACF$COUNT,ACF$T),var)

MPV documentation built on April 14, 2025, 9:07 a.m.

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