Mediana: Clinical Trial Simulations

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Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

Author
Gautier Paux, Alex Dmitrienko.
Date of publication
2016-08-25 10:28:07
Maintainer
Gautier Paux <gautier@paux.fr>
License
GPL-2
Version
1.0.3
URLs

View on CRAN

Man pages

AnalysisModel
AnalysisModel object
Criterion
Criterion object
CSE
Clinical Scenario Evaluation
CustomLabel
CustomLabel object
DataModel
DataModel object
DataStack
DataStack object
Design
Design object
EvaluationModel
EvaluationModel object
Event
Event object
ExtractDataStack
ExtractDataStack function
families
Create list of character strings
GenerateData
Generate data
GenerateReport
Clinical Scenario Evaluation Report
Mediana-package
Clinical Trial Simulations
MultAdj
MultAdj object
MultAdjProc
MultAdjProc object
MultAjdStrategy
MultAdjStrategy object
OutcomeDist
OutcomeDist object
PresentationModel
PresentationModel object
Project
Project object
Sample
Sample object
SampleSize
SampleSize object
Section
Section object
SimParameters
SimParameters object
Statistic
Statistic object
Subsection
Subsection object
Table
Table object
Test
Test object

Files in this package

Mediana
Mediana/NAMESPACE
Mediana/R
Mediana/R/CustomLabel.R
Mediana/R/MVExpoPFSOSDist.R
Mediana/R/CSE.R
Mediana/R/CreateDataScenarioEvent.R
Mediana/R/BonferroniAdj.global.R
Mediana/R/DiffPropStat.R
Mediana/R/HochbergAdj.R
Mediana/R/WilcoxTest.R
Mediana/R/AnalysisModel.MultAdjProc.R
Mediana/R/z+.EvaluationModel.R
Mediana/R/CreateTableCriterion.R
Mediana/R/HommelAdj.global.R
Mediana/R/ExpectedRejPower.R
Mediana/R/CreateEvaluationStructure.R
Mediana/R/CreateTableStatistic.R
Mediana/R/PresentationModel.R
Mediana/R/PresentationModel.CustomLabel.R
Mediana/R/PresentationModel.default.R
Mediana/R/MixtureGatekeepingAdj.R
Mediana/R/Subsection.R
Mediana/R/BinomDist.R
Mediana/R/MaxStat.R
Mediana/R/RatioEffectSizeEventStat.R
Mediana/R/Design.R
Mediana/R/AnalysisModel.R
Mediana/R/z+.AnalysisModel.R
Mediana/R/GenerateData.default.R
Mediana/R/BroadClaimPower.R
Mediana/R/EventCountStat.R
Mediana/R/CreateTableSampleSize.R
Mediana/R/DataModel.SampleSize.R
Mediana/R/NormalParamDist.R
Mediana/R/summary.CSE.R
Mediana/R/HolmAdj.R
Mediana/R/Test.R
Mediana/R/Event.R
Mediana/R/DataModel.R
Mediana/R/DiffMeanStat.R
Mediana/R/PerformAnalysis.R
Mediana/R/argmin.R
Mediana/R/MultAdj.MultAdjStrategy.R
Mediana/R/BetaDist.R
Mediana/R/CreateSummaryTable.R
Mediana/R/is.PresentationModel.R
Mediana/R/HolmAdj.global.R
Mediana/R/Statistic.R
Mediana/R/DataModel.default.R
Mediana/R/MedianStat.R
Mediana/R/MultAdjStrategy.R
Mediana/R/BonferroniAdj.R
Mediana/R/MedianSumm.R
Mediana/R/CreateDataScenarioSampleSize.R
Mediana/R/GenerateReport.R
Mediana/R/MinStat.R
Mediana/R/Sample.R
Mediana/R/SdStat.R
Mediana/R/CreateAnalysisStructure.R
Mediana/R/families.R
Mediana/R/NormalDist.R
Mediana/R/GLMPoissonTest.R
Mediana/R/CreateDataSlice.R
Mediana/R/seq_vector.R
Mediana/R/z+.PresentationModel.R
Mediana/R/AnalysisModel.MultAdjStrategy.R
Mediana/R/EffectSizeEventStat.R
Mediana/R/EffectSizeContStat.R
Mediana/R/mergeOutcomeParameter.R
Mediana/R/CSE.default.R
Mediana/R/AnalysisModel.Statistic.R
Mediana/R/statistics.R
Mediana/R/CreateTableStructure.R
Mediana/R/samples.R
Mediana/R/PoissonDist.R
Mediana/R/MultAdjStrategy.default.R
Mediana/R/MultAdj.R
Mediana/R/RestrictedClaimPower.R
Mediana/R/EvaluationModel.Criterion.R
Mediana/R/GLMNegBinomTest.R
Mediana/R/NormalParamAdj.R
Mediana/R/MultipleSequenceGatekeepingAdj.R
Mediana/R/capwords.R
Mediana/R/CreateDataStack.R
Mediana/R/PresentationModel.Section.R
Mediana/R/is.AnalysisModel.R
Mediana/R/is.EvaluationModel.R
Mediana/R/Interim.R
Mediana/R/LogrankTest.R
Mediana/R/errorfrac.R
Mediana/R/RatioEffectSizeContStat.R
Mediana/R/PropTestNI.R
Mediana/R/DataModel.Design.R
Mediana/R/UniformDist.R
Mediana/R/MVMixedDist.R
Mediana/R/CreateTableDesign.R
Mediana/R/Table.R
Mediana/R/CreateDataStructure.R
Mediana/R/Project.R
Mediana/R/z+.DataModel.R
Mediana/R/AnalysisModel.MultAdj.R
Mediana/R/NegBinomDist.R
Mediana/R/ExpoDist.R
Mediana/R/EnhancedClaimPower.R
Mediana/R/CreateReportStructure.R
Mediana/R/GeneratePatients.R
Mediana/R/WeightedPower.R
Mediana/R/AnalysisModel.Test.R
Mediana/R/DataModel.Event.R
Mediana/R/AnalysisModel.default.R
Mediana/R/TTestNI.R
Mediana/R/PresentationModel.Table.R
Mediana/R/MVBinomDist.R
Mediana/R/MVExpoDist.R
Mediana/R/CreateTableOutcome.R
Mediana/R/PatientCountStat.R
Mediana/R/FisherTest.R
Mediana/R/MultAdj.MultAdjProc.R
Mediana/R/CreateTableTest.R
Mediana/R/PropTest.R
Mediana/R/ChainAdj.R
Mediana/R/EvaluationModel.default.R
Mediana/R/PresentationModel.Project.R
Mediana/R/MeanSumm.R
Mediana/R/MarginalPower.R
Mediana/R/GenerateReport.default.R
Mediana/R/TruncatedExpoDist.R
Mediana/R/RatioEffectSizePropStat.R
Mediana/R/MultAdjStrategy.MultAdjProc.R
Mediana/R/ExtractDataStack.R
Mediana/R/DisjunctivePower.R
Mediana/R/GenerateData.R
Mediana/R/InteractionPower.R
Mediana/R/appendList.R
Mediana/R/DataStack.default.R
Mediana/R/HommelAdj.R
Mediana/R/PresentationModel.Subsection.R
Mediana/R/DataStack.R
Mediana/R/AnalysisModel.Interim.R
Mediana/R/ConjunctivePower.R
Mediana/R/is.DataModel.R
Mediana/R/HazardRatioStat.R
Mediana/R/InfluencePower.R
Mediana/R/EvaluationModel.R
Mediana/R/ParallelGatekeepingAdj.R
Mediana/R/TTest.R
Mediana/R/EffectSizePropStat.R
Mediana/R/OutcomeDist.R
Mediana/R/parameters.R
Mediana/R/MultAdjProc.R
Mediana/R/Criterion.R
Mediana/R/SampleSize.R
Mediana/R/SimParameters.R
Mediana/R/MeanStat.R
Mediana/R/tests.R
Mediana/R/Section.R
Mediana/R/MultAdj.default.R
Mediana/R/DataModel.OutcomeDist.R
Mediana/R/HochbergAdj.global.R
Mediana/R/MVNormalDist.R
Mediana/README.md
Mediana/MD5
Mediana/DESCRIPTION
Mediana/man
Mediana/man/SimParameters.Rd
Mediana/man/Criterion.Rd
Mediana/man/MultAdj.Rd
Mediana/man/Design.Rd
Mediana/man/GenerateReport.Rd
Mediana/man/families.Rd
Mediana/man/MultAjdStrategy.Rd
Mediana/man/CSE.Rd
Mediana/man/Subsection.Rd
Mediana/man/DataStack.Rd
Mediana/man/ExtractDataStack.Rd
Mediana/man/AnalysisModel.Rd
Mediana/man/Event.Rd
Mediana/man/EvaluationModel.Rd
Mediana/man/Test.Rd
Mediana/man/OutcomeDist.Rd
Mediana/man/Table.Rd
Mediana/man/GenerateData.Rd
Mediana/man/Sample.Rd
Mediana/man/CustomLabel.Rd
Mediana/man/PresentationModel.Rd
Mediana/man/Statistic.Rd
Mediana/man/Project.Rd
Mediana/man/DataModel.Rd
Mediana/man/SampleSize.Rd
Mediana/man/Section.Rd
Mediana/man/MultAdjProc.Rd
Mediana/man/Mediana-package.Rd