Mediana: Clinical Trial Simulations

Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

AuthorGautier Paux, Alex Dmitrienko.
Date of publication2017-02-07 10:08:33
MaintainerGautier Paux <gautier@paux.fr>
LicenseGPL-2
Version1.0.4
http://gpaux.github.io/Mediana/

View on CRAN

Functions

AnalysisModel Man page
Criterion Man page
CSE Man page
CustomLabel Man page
DataModel Man page
DataStack Man page
Design Man page
EvaluationModel Man page
Event Man page
ExtractDataStack Man page
families Man page
GenerateData Man page
GenerateReport Man page
Mediana Man page
Mediana-package Man page
MultAdj Man page
MultAdjProc Man page
MultAdjStrategy Man page
OutcomeDist Man page
parameters Man page
PresentationModel Man page
Project Man page
Sample Man page
samples Man page
SampleSize Man page
Section Man page
SimParameters Man page
Statistic Man page
statistics Man page
Subsection Man page
Table Man page
Test Man page
tests Man page

Files

Mediana
Mediana/NAMESPACE
Mediana/NEWS.md
Mediana/R
Mediana/R/CustomLabel.R Mediana/R/MVExpoPFSOSDist.R Mediana/R/CSE.R Mediana/R/CreateDataScenarioEvent.R Mediana/R/BonferroniAdj.global.R Mediana/R/DiffPropStat.R Mediana/R/FixedSeqAdj.R Mediana/R/HochbergAdj.R Mediana/R/WilcoxTest.R Mediana/R/AnalysisModel.MultAdjProc.R Mediana/R/z+.EvaluationModel.R Mediana/R/CreateTableCriterion.R Mediana/R/HommelAdj.global.R Mediana/R/ExpectedRejPower.R Mediana/R/CreateEvaluationStructure.R Mediana/R/CreateTableStatistic.R Mediana/R/PresentationModel.R Mediana/R/PresentationModel.CustomLabel.R Mediana/R/PresentationModel.default.R Mediana/R/MixtureGatekeepingAdj.R Mediana/R/Subsection.R Mediana/R/BinomDist.R Mediana/R/MaxStat.R Mediana/R/RatioEffectSizeEventStat.R Mediana/R/Design.R Mediana/R/AnalysisModel.R Mediana/R/z+.AnalysisModel.R Mediana/R/GenerateData.default.R Mediana/R/BroadClaimPower.R Mediana/R/EventCountStat.R Mediana/R/CreateTableSampleSize.R Mediana/R/DataModel.SampleSize.R Mediana/R/NormalParamDist.R Mediana/R/summary.CSE.R Mediana/R/HolmAdj.R Mediana/R/Test.R Mediana/R/Event.R Mediana/R/DataModel.R Mediana/R/DiffMeanStat.R Mediana/R/PerformAnalysis.R Mediana/R/argmin.R Mediana/R/MultAdj.MultAdjStrategy.R Mediana/R/BetaDist.R Mediana/R/CreateSummaryTable.R Mediana/R/is.PresentationModel.R Mediana/R/HolmAdj.global.R Mediana/R/Statistic.R Mediana/R/DataModel.default.R Mediana/R/MedianStat.R Mediana/R/MultAdjStrategy.R Mediana/R/BonferroniAdj.R Mediana/R/MedianSumm.R Mediana/R/CreateDataScenarioSampleSize.R Mediana/R/GenerateReport.R Mediana/R/MinStat.R Mediana/R/Sample.R Mediana/R/SdStat.R Mediana/R/CreateAnalysisStructure.R Mediana/R/families.R Mediana/R/NormalDist.R Mediana/R/GLMPoissonTest.R Mediana/R/CreateDataSlice.R Mediana/R/seq_vector.R Mediana/R/z+.PresentationModel.R Mediana/R/AnalysisModel.MultAdjStrategy.R Mediana/R/EffectSizeEventStat.R Mediana/R/EffectSizeContStat.R Mediana/R/mergeOutcomeParameter.R Mediana/R/CSE.default.R Mediana/R/AnalysisModel.Statistic.R Mediana/R/statistics.R Mediana/R/CreateTableStructure.R Mediana/R/samples.R Mediana/R/PoissonDist.R Mediana/R/MultAdjStrategy.default.R Mediana/R/MultAdj.R Mediana/R/RestrictedClaimPower.R Mediana/R/EvaluationModel.Criterion.R Mediana/R/GLMNegBinomTest.R Mediana/R/HazardRatioCoxStat.R Mediana/R/NormalParamAdj.R Mediana/R/MultipleSequenceGatekeepingAdj.R Mediana/R/capwords.R Mediana/R/CreateDataStack.R Mediana/R/PresentationModel.Section.R Mediana/R/is.AnalysisModel.R Mediana/R/is.EvaluationModel.R Mediana/R/Interim.R Mediana/R/RatioEffectSizeCoxEventStat.R Mediana/R/LogrankTest.R Mediana/R/errorfrac.R Mediana/R/RatioEffectSizeContStat.R Mediana/R/PropTestNI.R Mediana/R/DataModel.Design.R Mediana/R/UniformDist.R Mediana/R/MVMixedDist.R Mediana/R/CreateTableDesign.R Mediana/R/Table.R Mediana/R/CreateDataStructure.R Mediana/R/Project.R Mediana/R/z+.DataModel.R Mediana/R/AnalysisModel.MultAdj.R Mediana/R/NegBinomDist.R Mediana/R/ExpoDist.R Mediana/R/EnhancedClaimPower.R Mediana/R/CreateReportStructure.R Mediana/R/GeneratePatients.R Mediana/R/WeightedPower.R Mediana/R/AnalysisModel.Test.R Mediana/R/DataModel.Event.R Mediana/R/AnalysisModel.default.R Mediana/R/TTestNI.R Mediana/R/PresentationModel.Table.R Mediana/R/MVBinomDist.R Mediana/R/MVExpoDist.R Mediana/R/CreateTableOutcome.R Mediana/R/PatientCountStat.R Mediana/R/FisherTest.R Mediana/R/MultAdj.MultAdjProc.R Mediana/R/CreateTableTest.R Mediana/R/PropTest.R Mediana/R/ChainAdj.R Mediana/R/EvaluationModel.default.R Mediana/R/PresentationModel.Project.R Mediana/R/MeanSumm.R Mediana/R/MarginalPower.R Mediana/R/GenerateReport.default.R Mediana/R/TruncatedExpoDist.R Mediana/R/RatioEffectSizePropStat.R Mediana/R/MultAdjStrategy.MultAdjProc.R Mediana/R/ExtractDataStack.R Mediana/R/DisjunctivePower.R Mediana/R/GenerateData.R Mediana/R/InteractionPower.R Mediana/R/appendList.R Mediana/R/DataStack.default.R Mediana/R/HommelAdj.R Mediana/R/PresentationModel.Subsection.R Mediana/R/DataStack.R Mediana/R/AnalysisModel.Interim.R Mediana/R/ConjunctivePower.R Mediana/R/is.DataModel.R Mediana/R/HazardRatioStat.R Mediana/R/InfluencePower.R Mediana/R/EvaluationModel.R Mediana/R/ParallelGatekeepingAdj.R Mediana/R/TTest.R Mediana/R/EffectSizePropStat.R Mediana/R/EffectSizeCoxEventStat.R Mediana/R/OutcomeDist.R Mediana/R/parameters.R Mediana/R/MultAdjProc.R Mediana/R/Criterion.R Mediana/R/SampleSize.R Mediana/R/SimParameters.R Mediana/R/MeanStat.R Mediana/R/tests.R Mediana/R/Section.R Mediana/R/MultAdj.default.R Mediana/R/DataModel.OutcomeDist.R Mediana/R/HochbergAdj.global.R Mediana/R/MVNormalDist.R
Mediana/README.md
Mediana/MD5
Mediana/DESCRIPTION
Mediana/man
Mediana/man/SimParameters.Rd Mediana/man/Criterion.Rd Mediana/man/MultAdj.Rd Mediana/man/Design.Rd Mediana/man/GenerateReport.Rd Mediana/man/families.Rd Mediana/man/MultAjdStrategy.Rd Mediana/man/CSE.Rd Mediana/man/Subsection.Rd Mediana/man/DataStack.Rd Mediana/man/ExtractDataStack.Rd Mediana/man/AnalysisModel.Rd Mediana/man/Event.Rd Mediana/man/EvaluationModel.Rd Mediana/man/Test.Rd Mediana/man/OutcomeDist.Rd Mediana/man/Table.Rd Mediana/man/GenerateData.Rd Mediana/man/Sample.Rd Mediana/man/CustomLabel.Rd Mediana/man/PresentationModel.Rd Mediana/man/Statistic.Rd Mediana/man/Project.Rd Mediana/man/DataModel.Rd Mediana/man/SampleSize.Rd Mediana/man/Section.Rd Mediana/man/MultAdjProc.Rd Mediana/man/Mediana-package.Rd

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

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