Mediana: Clinical Trial Simulations
Version 1.0.4

Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

AuthorGautier Paux, Alex Dmitrienko.
Date of publication2017-02-07 10:08:33
MaintainerGautier Paux <gautier@paux.fr>
LicenseGPL-2
Version1.0.4
URL http://gpaux.github.io/Mediana/
Package repositoryView on CRAN
InstallationInstall the latest version of this package by entering the following in R:
install.packages("Mediana")

Getting started

Package overview
README.md

Popular man pages

Criterion: Criterion object
CSE: Clinical Scenario Evaluation
DataStack: DataStack object
families: Create list of character strings
Mediana-package: Clinical Trial Simulations
Project: Project object
Section: Section object
See all...

All man pages Function index File listing

Man pages

AnalysisModel: AnalysisModel object
Criterion: Criterion object
CSE: Clinical Scenario Evaluation
CustomLabel: CustomLabel object
DataModel: DataModel object
DataStack: DataStack object
Design: Design object
EvaluationModel: EvaluationModel object
Event: Event object
ExtractDataStack: ExtractDataStack function
families: Create list of character strings
GenerateData: Generate data
GenerateReport: Clinical Scenario Evaluation Report
Mediana-package: Clinical Trial Simulations
MultAdj: MultAdj object
MultAdjProc: MultAdjProc object
MultAjdStrategy: MultAdjStrategy object
OutcomeDist: OutcomeDist object
PresentationModel: PresentationModel object
Project: Project object
Sample: Sample object
SampleSize: SampleSize object
Section: Section object
SimParameters: SimParameters object
Statistic: Statistic object
Subsection: Subsection object
Table: Table object
Test: Test object

Functions

AnalysisModel Man page Source code
AnalysisModel.Interim Source code
AnalysisModel.MultAdj Source code
AnalysisModel.MultAdjProc Source code
AnalysisModel.MultAdjStrategy Source code
AnalysisModel.Statistic Source code
AnalysisModel.Test Source code
AnalysisModel.default Source code
BetaDist Source code
BinomDist Source code
BonferroniAdj Source code
BonferroniAdj.global Source code
BroadClaimPower Source code
CSE Man page Source code
CSE.default Source code
ChainAdj Source code
ConjunctivePower Source code
CreateAnalysisStructure Source code
CreateDataScenarioEvent Source code
CreateDataScenarioSampleSize Source code
CreateDataSlice Source code
CreateDataStack Source code
CreateDataStructure Source code
CreateEvaluationStructure Source code
CreateReportStructure Source code
CreateSummaryTable Source code
CreateTableCriterion Source code
CreateTableDesign Source code
CreateTableOutcome Source code
CreateTableSampleSize Source code
CreateTableStatistic Source code
CreateTableStructure Source code
CreateTableTest Source code
Criterion Man page Source code
CustomLabel Man page Source code
DataModel Man page Source code
DataModel.Design Source code
DataModel.Event Source code
DataModel.OutcomeDist Source code
DataModel.SampleSize Source code
DataModel.default Source code
DataStack Man page Source code
DataStack.default Source code
Design Man page Source code
DiffMeanStat Source code
DiffPropStat Source code
DisjunctivePower Source code
EffectSizeContStat Source code
EffectSizeCoxEventStat Source code
EffectSizeEventStat Source code
EffectSizePropStat Source code
EnhancedClaimPower Source code
EvaluationModel Man page Source code
EvaluationModel.Criterion Source code
EvaluationModel.default Source code
Event Man page Source code
EventCountStat Source code
ExpectedRejPower Source code
ExpoDist Source code
ExtractDataStack Man page Source code
FisherTest Source code
FixedSeqAdj Source code
GLMNegBinomTest Source code
GLMPoissonTest Source code
GenerateData Man page Source code
GenerateData.default Source code
GeneratePatients Source code
GenerateReport Man page Source code
GenerateReport.default Source code
HazardRatioCoxStat Source code
HazardRatioStat Source code
HochbergAdj Source code
HochbergAdj.global Source code
HolmAdj Source code
HolmAdj.global Source code
HommelAdj Source code
HommelAdj.global Source code
InfluencePower Source code
InteractionPower Source code
Interim Source code
LogrankTest Source code
MVBinomDist Source code
MVExpoDist Source code
MVExpoPFSOSDist Source code
MVMixedDist Source code
MVNormalDist Source code
MarginalPower Source code
MaxStat Source code
MeanStat Source code
MeanSumm Source code
MedianStat Source code
MedianSumm Source code
Mediana Man page
Mediana-package Man page
MinStat Source code
MixtureGatekeepingAdj Source code
MultAdj Man page Source code
MultAdj.MultAdjProc Source code
MultAdj.MultAdjStrategy Source code
MultAdj.default Source code
MultAdjProc Man page Source code
MultAdjStrategy Man page Source code
MultAdjStrategy.MultAdjProc Source code
MultAdjStrategy.default Source code
MultipleSequenceGatekeepingAdj Source code
NegBinomDist Source code
NormalDist Source code
NormalParamAdj Source code
NormalParamDist Source code
OutcomeDist Man page Source code
ParallelGatekeepingAdj Source code
PatientCountStat Source code
PerformAnalysis Source code
PoissonDist Source code
PresentationModel Man page Source code
PresentationModel.CustomLabel Source code
PresentationModel.Project Source code
PresentationModel.Section Source code
PresentationModel.Subsection Source code
PresentationModel.Table Source code
PresentationModel.default Source code
Project Man page Source code
PropTest Source code
PropTestNI Source code
RatioEffectSizeContStat Source code
RatioEffectSizeCoxEventStat Source code
RatioEffectSizeEventStat Source code
RatioEffectSizePropStat Source code
RestrictedClaimPower Source code
Sample Man page Source code
SampleSize Man page Source code
SdStat Source code
Section Man page Source code
SimParameters Man page Source code
Statistic Man page Source code
Subsection Man page Source code
TTest Source code
TTestNI Source code
Table Man page Source code
Test Man page Source code
TruncatedExpoDist Source code
UniformDist Source code
WeightedPower Source code
WilcoxTest Source code
appendList Source code
argmin Source code
capwords Source code
errorfrac Source code
families Man page Source code
is.AnalysisModel Source code
is.DataModel Source code
is.EvaluationModel Source code
is.PresentationModel Source code
mergeOutcomeParameter Source code
parameters Man page Source code
samples Man page Source code
seq_vector Source code
statistics Man page Source code
summary.CSE Source code
tests Man page Source code

Files

NAMESPACE
NEWS.md
R
R/CustomLabel.R
R/MVExpoPFSOSDist.R
R/CSE.R
R/CreateDataScenarioEvent.R
R/BonferroniAdj.global.R
R/DiffPropStat.R
R/FixedSeqAdj.R
R/HochbergAdj.R
R/WilcoxTest.R
R/AnalysisModel.MultAdjProc.R
R/z+.EvaluationModel.R
R/CreateTableCriterion.R
R/HommelAdj.global.R
R/ExpectedRejPower.R
R/CreateEvaluationStructure.R
R/CreateTableStatistic.R
R/PresentationModel.R
R/PresentationModel.CustomLabel.R
R/PresentationModel.default.R
R/MixtureGatekeepingAdj.R
R/Subsection.R
R/BinomDist.R
R/MaxStat.R
R/RatioEffectSizeEventStat.R
R/Design.R
R/AnalysisModel.R
R/z+.AnalysisModel.R
R/GenerateData.default.R
R/BroadClaimPower.R
R/EventCountStat.R
R/CreateTableSampleSize.R
R/DataModel.SampleSize.R
R/NormalParamDist.R
R/summary.CSE.R
R/HolmAdj.R
R/Test.R
R/Event.R
R/DataModel.R
R/DiffMeanStat.R
R/PerformAnalysis.R
R/argmin.R
R/MultAdj.MultAdjStrategy.R
R/BetaDist.R
R/CreateSummaryTable.R
R/is.PresentationModel.R
R/HolmAdj.global.R
R/Statistic.R
R/DataModel.default.R
R/MedianStat.R
R/MultAdjStrategy.R
R/BonferroniAdj.R
R/MedianSumm.R
R/CreateDataScenarioSampleSize.R
R/GenerateReport.R
R/MinStat.R
R/Sample.R
R/SdStat.R
R/CreateAnalysisStructure.R
R/families.R
R/NormalDist.R
R/GLMPoissonTest.R
R/CreateDataSlice.R
R/seq_vector.R
R/z+.PresentationModel.R
R/AnalysisModel.MultAdjStrategy.R
R/EffectSizeEventStat.R
R/EffectSizeContStat.R
R/mergeOutcomeParameter.R
R/CSE.default.R
R/AnalysisModel.Statistic.R
R/statistics.R
R/CreateTableStructure.R
R/samples.R
R/PoissonDist.R
R/MultAdjStrategy.default.R
R/MultAdj.R
R/RestrictedClaimPower.R
R/EvaluationModel.Criterion.R
R/GLMNegBinomTest.R
R/HazardRatioCoxStat.R
R/NormalParamAdj.R
R/MultipleSequenceGatekeepingAdj.R
R/capwords.R
R/CreateDataStack.R
R/PresentationModel.Section.R
R/is.AnalysisModel.R
R/is.EvaluationModel.R
R/Interim.R
R/RatioEffectSizeCoxEventStat.R
R/LogrankTest.R
R/errorfrac.R
R/RatioEffectSizeContStat.R
R/PropTestNI.R
R/DataModel.Design.R
R/UniformDist.R
R/MVMixedDist.R
R/CreateTableDesign.R
R/Table.R
R/CreateDataStructure.R
R/Project.R
R/z+.DataModel.R
R/AnalysisModel.MultAdj.R
R/NegBinomDist.R
R/ExpoDist.R
R/EnhancedClaimPower.R
R/CreateReportStructure.R
R/GeneratePatients.R
R/WeightedPower.R
R/AnalysisModel.Test.R
R/DataModel.Event.R
R/AnalysisModel.default.R
R/TTestNI.R
R/PresentationModel.Table.R
R/MVBinomDist.R
R/MVExpoDist.R
R/CreateTableOutcome.R
R/PatientCountStat.R
R/FisherTest.R
R/MultAdj.MultAdjProc.R
R/CreateTableTest.R
R/PropTest.R
R/ChainAdj.R
R/EvaluationModel.default.R
R/PresentationModel.Project.R
R/MeanSumm.R
R/MarginalPower.R
R/GenerateReport.default.R
R/TruncatedExpoDist.R
R/RatioEffectSizePropStat.R
R/MultAdjStrategy.MultAdjProc.R
R/ExtractDataStack.R
R/DisjunctivePower.R
R/GenerateData.R
R/InteractionPower.R
R/appendList.R
R/DataStack.default.R
R/HommelAdj.R
R/PresentationModel.Subsection.R
R/DataStack.R
R/AnalysisModel.Interim.R
R/ConjunctivePower.R
R/is.DataModel.R
R/HazardRatioStat.R
R/InfluencePower.R
R/EvaluationModel.R
R/ParallelGatekeepingAdj.R
R/TTest.R
R/EffectSizePropStat.R
R/EffectSizeCoxEventStat.R
R/OutcomeDist.R
R/parameters.R
R/MultAdjProc.R
R/Criterion.R
R/SampleSize.R
R/SimParameters.R
R/MeanStat.R
R/tests.R
R/Section.R
R/MultAdj.default.R
R/DataModel.OutcomeDist.R
R/HochbergAdj.global.R
R/MVNormalDist.R
README.md
MD5
DESCRIPTION
man
man/SimParameters.Rd
man/Criterion.Rd
man/MultAdj.Rd
man/Design.Rd
man/GenerateReport.Rd
man/families.Rd
man/MultAjdStrategy.Rd
man/CSE.Rd
man/Subsection.Rd
man/DataStack.Rd
man/ExtractDataStack.Rd
man/AnalysisModel.Rd
man/Event.Rd
man/EvaluationModel.Rd
man/Test.Rd
man/OutcomeDist.Rd
man/Table.Rd
man/GenerateData.Rd
man/Sample.Rd
man/CustomLabel.Rd
man/PresentationModel.Rd
man/Statistic.Rd
man/Project.Rd
man/DataModel.Rd
man/SampleSize.Rd
man/Section.Rd
man/MultAdjProc.Rd
man/Mediana-package.Rd
Mediana documentation built on May 20, 2017, 6:04 a.m.

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