MultAdj: MultAdj object

In Mediana: Clinical Trial Simulations

Description

This function creates an object of class MultAdj which can be added to an object of class AnalysisModel.

Usage

MultAdj(...)

Arguments

...	defines the arguments passed to create the object of class MultAdj.

Details

This function can be used to wrap-up several objects of class MultAdjProc or MultAdjStrategy and add them to an object of class AnalysisModel. Its use is optional as objects of class MultAdjProc or MultAdjStrategy can be added to an object of class AnalysisModel incrementally using the '+' operator.

Objects of class MultAdjProc or MultAdjStrategy can be added to an object of class AnalysisModel.

References

http://gpaux.github.io/Mediana/

See Also

See Also MultAdjStrategy, MultAdjProc and AnalysisModel.

Examples

# Multiplicity adjustments
mult.adj1 = MultAdjProc(proc = NA)
mult.adj2 = MultAdjProc(proc = "BonferroniAdj")
mult.adj3 = MultAdjProc(proc = "HolmAdj", par = parameters(weight = rep(1/3,3)))
mult.adj4 = MultAdjProc(proc = "HochbergAdj", par = parameters(weight = c(1/4,1/4,1/2)))


# Analysis model
analysis.model = AnalysisModel() +
                 MultAdj(mult.adj1, mult.adj2, mult.adj3, mult.adj4) +
                 Test(id = "Pl vs Dose L",
                      samples = samples("Placebo", "Dose L"),
                      method = "TTest") +
                 Test(id = "Pl vs Dose M",
                      samples = samples ("Placebo", "Dose M"),
                      method = "TTest") +
                 Test(id = "Pl vs Dose H",
                      samples = samples("Placebo", "Dose H"),
                      method = "TTest")

# Equivalent to:
analysis.model = AnalysisModel() +
                 mult.adj1 +
                 mult.adj2 +
                 mult.adj3 +
                 mult.adj4 +
                 Test(id = "Pl vs Dose L",
                      samples = samples("Placebo", "Dose L"),
                      method = "TTest") +
                 Test(id = "Pl vs Dose M",
                      samples = samples ("Placebo", "Dose M"),
                      method = "TTest") +
                 Test(id = "Pl vs Dose H",
                      samples = samples("Placebo", "Dose H"),
                      method = "TTest")

Mediana documentation built on May 8, 2019, 5:04 p.m.