This function computes each element of the matrix function DD_weight_2 which is the second derivative of the Ds-optimality criterion with respect to the model parameters.
1 |
T |
A numeric vector. Model parameter values |
x1 |
A numeric. ith dose level for a given design |
x2 |
A numeric. jth dose level for a given design |
xl |
A numeric. last dose level for a given design |
inv |
A numeric matrix. Inverse of the information matrix for the 5PL model |
inv1 |
A numeric matrix. Inverse of the information matrix for the 4PL model |
order |
numeric. The number of model paraemters |
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