This computes the first derivative of the D-optimality criterion with respect to the model parameters for a specified model.
1 |
T |
A numeric vector. Model parameter values |
x |
A numeric. ith dose level |
xl |
A numeric. last dose level |
inv |
A numeric matrix. Inverse infromation matrix |
order |
numeric. The number of model paraemters: 3, 4, 5 for the 3, 4, 5PL models respectively |
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