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PFIM: Population Fisher Information Matrix
Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>, Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>, Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>, Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>, Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.
Getting started
Browse package contents
Package details |
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| Author | France Mentré [aut], Romain Leroux [aut, cre], Jérémy Seurat [aut], Lucie Fayette [aut] |
| Maintainer | Romain Leroux <romain.leroux@inserm.fr> |
| License | GPL (>= 2) |
| Version | 6.1 |
| URL | http://www.pfim.biostat.fr/ |
| Package repository | View on CRAN |
| Installation |
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