Man pages for PFIM
Population Fisher Information Matrix
| adjustGradient | adjustGradient: adjust the gradient for the log normal... |
| Administration | Administration |
| AdministrationConstraints | AdministrationConstraints |
| Arm | Arm |
| armAdministration | getArmAdministration: get the administration parameters of an... |
| BayesianFim | BayesianFim |
| checkSamplingTimeConstraintsForMetaheuristic | checkSamplingTimeConstraintsForMetaheuristic |
| checkValiditySamplingConstraint | checkValiditySamplingConstraint: check if the constraints... |
| Combined1 | Combined1 |
| computeVMat | computeVMat |
| Constant | Constant |
| constraintsTableForReport | constraintsTableForReport: table of the PGBOAlgorithm... |
| convertPKModelAnalyticToPKModelODE | convertPKModelAnalyticToPKModelODE: conversion from analytic... |
| Dcriterion | Dcriterion: get the D-criterion of the Fim. |
| defineFim | define the type of Fisher information matrix: population,... |
| defineModelAdministration | defineModelAdministration: define the administration |
| defineModelEquationsFromLibraryOfModel | defineModelEquationsFromLibraryOfModel: define the model... |
| defineModelType | defineModelType: define the class of the model to be... |
| defineModelWrapper | defineModelWrapper: define the model wrapper for the ode... |
| defineOptimizationAlgorithm | Define optimization algorithm |
| definePKModel | definePKModel: define a PK model from library of model |
| definePKPDModel | definePKPDModel: define a PKPD model from library of model |
| Design | Design |
| Distribution | Distribution |
| evaluateArm | evaluateArm: evaluation of the model with the arm parameters. |
| evaluateDesign | evaluateDesign: evaluation of a design. |
| evaluateErrorModelDerivatives | evaluateErrorModelDerivatives; evaluate the derivatives of... |
| evaluateFim | evaluateFim: evaluation of the Fim |
| evaluateInitialConditions | evaluateInitialConditions: evaluate the initial conditions. |
| evaluateModel | evaluateModel: evaluate the model |
| evaluateModelGradient | evaluateModelGradient: evaluate the gradient of the model |
| evaluateModelVariance | evaluateModelVariance: evaluate the variance of the model |
| evaluateVarianceFIM | evaluateVarianceFIM: evaluate the variance |
| Evaluation | Evaluation |
| FedorovWynnAlgorithm | FedorovWynnAlgorithm |
| FedorovWynnAlgorithm_Rcpp | Fedorov-Wynn algorithm in Rcpp. |
| Fim | Fim |
| finiteDifferenceHessian | finiteDifferenceHessian: compute the Hessian |
| fisherSimplex | Compute the fisher.simplex |
| fun.amoeba | Compute the fun.amoeba |
| generateDosesCombination | generateDosesCombination: generate the combination for the... |
| generateFimsFromConstraints | Generate FIMs from constraints |
| generateReportEvaluation | generateReportEvaluation: generate the report for the model... |
| generateReportOptimization | generateReportOptimization: generate the report for the... |
| generateSamplingsFromSamplingConstraints | generateSamplingsFromSamplingConstraints |
| generateSamplingTimesCombination | generateSamplingTimesCombination: generate the combination... |
| getArmConstraints | getArmConstraints: get the administration and sampling time... |
| getArmData | getArmData: extract arm data for The Report |
| getCorrelationMatrix | getCorrelationMatrix : get the correlation matrix |
| getDcriterion | getDcriterion : get the Dcriterion |
| getDeterminant | getDeterminant: get the determinant |
| getFim | getFim: get the Fisher matrix. |
| getFisherMatrix | getFisherMatrix: display the Fisher matrix components |
| getListLastName | getListLastName: routine to get the names of last element of... |
| getModelErrorData | getModelErrorData: get the parameters sigma slope and sigma... |
| getModelParametersData | getModelParametersData: get model parameters data for report. |
| getRSE | getRSE: get the RSE |
| getSamplingData | getSamplingData: extract sampling times and max sampling time... |
| getSE | getSE: get the SE |
| getShrinkage | getShrinkage: get the shrinkage |
| IndividualFim | IndividualFim |
| LibraryOfModels | LibraryOfModels |
| LibraryOfPDModels | LibraryOfPDModels |
| LibraryOfPKModels | LibraryOfPKModels |
| Linear2BolusSingleDose_ClQV1V2 | Model Linear2BolusSingleDose_ClQV1V2 |
| Linear2BolusSingleDose_kk12k21V | Model Linear2BolusSingleDose_kk12k21V |
| Linear2BolusSteadyState_ClQV1V2tau | Model Linear2BolusSteadyState_ClQV1V2tau |
| Linear2BolusSteadyState_kk12k21Vtau | Model Linear2BolusSteadyState_kk12k21Vtau |
| Linear2FirstOrderSingleDose_kaClQV1V2 | Model Linear2FirstOrderSingleDose_kaClQV1V2 |
| Linear2FirstOrderSingleDose_kakk12k21V | Model Linear2FirstOrderSingleDose_kakk12k21V |
| Linear2FirstOrderSteadyState_kaClQV1V2tau | Model Linear2FirstOrderSteadyState_kaClQV1V2tau |
| Linear2FirstOrderSteadyState_kakk12k21Vtau | Model Linear2FirstOrderSteadyState_kakk12k21Vtau |
| Linear2InfusionSingleDose_ClQV1V2 | Model Linear2InfusionSingleDose_ClQV1V2 |
| Linear2InfusionSingleDose_kk12k21V | Model Linear2InfusionSingleDose_kk12k21V |
| Linear2InfusionSteadyState_ClQV1V2tau | Model Linear2InfusionSteadyState_ClQV1V2tau |
| Linear2InfusionSteadyState_kk12k21Vtau | Model Linear2InfusionSteadyState_kk12k21Vtau |
| LogNormal | LogNormal |
| Model | Model |
| ModelAnalytic | ModelAnalytic |
| ModelAnalyticInfusion | ModelAnalyticInfusion |
| ModelAnalyticInfusionSteadyState | ModelAnalyticInfusionSteadyState |
| ModelAnalyticSteadyState | ModelAnalyticSteadyState |
| ModelError | ModelError |
| ModelInfusion | ModelInfusion |
| ModelODE | ModelODE |
| ModelODEBolus | ModelODEBolus |
| ModelODEDoseInEquations | ModelODEDoseNotInEquations |
| ModelODEDoseNotInEquations | ModelODEDoseNotInEquations |
| ModelODEInfusion | ModelODEInfusion |
| ModelODEInfusionDoseInEquation | ModelODEInfusionDoseInEquation |
| ModelParameter | ModelParameter |
| MultiplicativeAlgorithm | MultiplicativeAlgorithm |
| MultiplicativeAlgorithm_Rcpp | Function MultiplicativeAlgorithm_Rcpp |
| Normal | Normal |
| Optimization | Optimization |
| optimizeDesign | Optimization PGBOAlgorithm |
| PFIM-package | Fisher Information matrix for design evaluation/optimization... |
| PFIMProject | PFIMProject |
| PGBOAlgorithm | PGBOAlgorithm |
| plotEvaluation | plotEvaluation: plots for the evaluation of the model... |
| plotEvaluationResults | plotEvaluationResults: process for the evaluation of the... |
| plotEvaluationSI | plotEvaluationSI: process for the evaluation of the gradient... |
| plotFrequencies | Plot frequencies for the FedorovWynn algorithm |
| plotFrequenciesFedorovWynnAlgorithm | plotFrequenciesFedorovWynnAlgorithm |
| plotRSE | Plot relative standard errors |
| plotRSEFIM | plotRSEFIM: barplot for the RSE |
| plotSE | Plot standard errors |
| plotSEFIM | plotSEFIM: barplot for the SE |
| plotSensitivityIndices | Plot sensitivity indices. |
| plotShrinkage | plotShrinkage: plot the shrinkage values. |
| plotWeights | Plot weights for the multiplicative algorithm |
| plotWeightsMultiplicativeAlgorithm | plotWeightsMultiplicativeAlgorithm: plot the optimal weight. |
| PopulationFim | PopulationFim |
| processArmEvaluationResults | processArmEvaluationResults: process for the evaluation of an... |
| processArmEvaluationSI | processArmEvaluationSI: process for the evaluation of the... |
| Proportional | Proportional |
| PSOAlgorithm | PSOAlgorithm |
| replaceVariablesLibraryOfModels | replaceVariablesLibraryOfModels: replace variable in the... |
| Report | Generate optimization report |
| run | Run optimization |
| SamplingTimeConstraints | SamplingTimeConstraints |
| SamplingTimes | SamplingTimes |
| setEvaluationFim | setEvaluationFim: set the Fim results. |
| setOptimalArms | setOptimalArms: set the optimal arms of an optimization... |
| setSamplingConstraintForOptimization | setSamplingConstraintForOptimization: set the sampling time... |
| show | Show optimization results |
| showFIM | showFIM: show the Fim in the R console. |
| SimplexAlgorithm | SimplexAlgorithm |
| tablesForReport | tablesForReport: generate the table for the report. |
| updateSamplingTimes | updateSamplingTimes: update sampling times for plotting used... |
