fit_var: Estimate Additive and proportional errors from calibration...

In PKbioanalysis: Pharmacokinetic Bioanalysis Experiments Design and Exploration

Estimate Additive and proportional errors from calibration data

Description

Estimate Additive and proportional errors from calibration data

Usage

fit_var(
  data,
  level = 0.95,
  method = "nlminb",
  bootstrap = FALSE,
  n_boot = 1000
)

Arguments

data	Data frame with columns: conc (concentration), stdconc (standardized concentration, e.g. conc/LLOQ)
level	Confidence level for the CI (default is 0.95)
method	Optimization method (default is "nlminb")
bootstrap	Logical indicating whether to perform bootstrap (default is TRUE)
n_boot	Number of bootstrap samples (default is 1000)

Author(s)

Omar I. Elashkar

PKbioanalysis documentation built on Jan. 15, 2026, 1:06 a.m.