PLIS: Multiplicity control using Pooled LIS statistic
Version 1.1

PLIS is a multiple testing procedure for testing several groups of hypotheses. Linear dependency is expected from the hypotheses within the same group and is modeled by hidden Markov Models. It is noted that, for PLIS, a smaller p value does not necessarily imply more significance because of dependency among the hypotheses. A typical application of PLIS is to analyze genome wide association studies datasets, where SNPs from the same chromosome are treated as a group and exhibit strong linear genomic dependency.

Package details

AuthorZhi Wei & Wenguang Sun
Date of publication2012-08-11 04:40:46
MaintainerZhi Wei <>
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:

Try the PLIS package in your browser

Any scripts or data that you put into this service are public.

PLIS documentation built on May 29, 2017, 5:46 p.m.