This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.
Package details |
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Author | Markus Boenn (State Office for Consumer Protection Saxony-Anhalt, Germany) |
Maintainer | Markus Boenn <markus.boenn.sf@gmail.com> |
License | GPL-3 |
Version | 1.2.0 |
Package repository | View on CRAN |
Installation |
Install the latest version of this package by entering the following in R:
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