This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematicalstatistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s0076901511129>.
Package details 


Author  Markus Boenn (State Office for Consumer Protection SaxonyAnhalt, Germany) 
Maintainer  Markus Boenn <[email protected]> 
License  GPL3 
Version  1.1.4 
Package repository  View on CRAN 
Installation 
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