computePOD: Compute the Probability Of Detection (POD)

In POD: Probability of Detection for Qualitative PCR Methods

Description

Compute the Probability Of Detection (POD) in qualitative PCR experiments carried out by a single laboratory.

Usage

computePOD(x, lambda = 1, b = 1)

Arguments

x	Nominal DNA concentrations (numeric vector)
lambda	The fraction of detected DNA fragments (numeric scalar)
b	correction parameter (numeric scalar)

Value

The POD function as described in Uhlig et al., 2015

References

Uhlig et al. Accred Qual Assur (2015) 20: 75. https://doi.org/10.1007/s00769-015-1112-9

Examples

# the optimal POD
computePOD(exp(seq(1, 10, 1)), 1, 1)
# some other POD
computePOD(exp(seq(1, 10, 1)), 0.5, 1.29)

Example output

##  PPP    OO   DDD
##  P  P  O  O  D  D
##  PPP  O    O D   D
##  P     O  O  D  D
##  P      OO   DDD
##
##  Loading package 'POD' version 1.2.0.
##  Type help(package=POD) for help.
##  Type citation(package='POD') for citation.
##  For your suggestions and bug-reports please contact: <[e-mail]>
##  Latest patches can also be found at: <https://github.com/markusboenn/POD>
##  
 [1] 0.934012 0.999382 1.000000 1.000000 1.000000 1.000000 1.000000 1.000000
 [9] 1.000000 1.000000
 [1] 0.8373888 0.9986377 1.0000000 1.0000000 1.0000000 1.0000000 1.0000000
 [8] 1.0000000 1.0000000 1.0000000

POD documentation built on July 2, 2020, 3:16 a.m.