PROFANCY: The package can prioritize candidate disease metabolites based on global functional relationships between metabolites in the context of metabolic pathways

The package can prioritize the candidate disease metabolites based on the assumption that functionally related metabolites tend to associate with the same or similar diseases in the context of metabolic pathway. The PROFANCY package (1) prioritizes the disease metabolites from global functional similarity and local modularity of the metabolic network; (2) allows users to select default metabolites or input their interested metabolites as seed nodes or candidate nodes (3) can prioritize the candidate metabolites in KEGG or EHMN metabolic network.

Package details

AuthorQianlan Yao, Desi Shang, Chunquan Li
Bioconductor views Disease Metabolites Network RandomWalk;
MaintainerQianlan Yao <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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PROFANCY documentation built on May 29, 2017, 12:37 p.m.