PSM: Non-Linear Mixed-Effects modelling using Stochastic Differential Equations.

This package provides functions for estimation of linear and non-linear mixed-effects models using stochastic differential equations. Moreover it provides functions for finding smoothed estimates of model states and for simulation. The package allows for any multivariate non-linear time-variant model to be specified, and it also handles multidimensional input, co-variates, missing observations and specification of dosage regimen.

Author
Stig Bousgaard Mortensen <stigbm@gmail.com> and Sren Klim <soren@klimens.dk>
Date of publication
2013-09-10 20:16:22
Maintainer
Stig Bousgaard Mortensen <stigbm@gmail.com>
License
GPL (>= 2)
Version
0.8-10
URLs

View on CRAN

Man pages

matexp
Matrix exponential
PSM.estimate
Estimate population parameters
PSM-internal
Internal functions in the PSM-package.
PSM-package
Population Stochastic Modelling
PSM.plot
Basic plots of data and output
PSM.simulate
Create simulation data for multiple individuals
PSM.smooth
Smoothing of model states based on estimated population...
PSM.template
Creates a template for a model in PSM

Files in this package

PSM
PSM/inst
PSM/inst/doc
PSM/inst/doc/PSM.pdf
PSM/inst/doc/PSM.R
PSM/inst/doc/PSM.Rnw
PSM/src
PSM/src/Makevars
PSM/src/matutil95.f95
PSM/src/matutil77.f
PSM/src/LTI_KALMAN.f95
PSM/src/matexp.f
PSM/NAMESPACE
PSM/R
PSM/R/PSM.template.R
PSM/R/APL.KF.individualloop.R
PSM/R/PSM.estimate.R
PSM/R/logit.R
PSM/R/ModelCheck.R
PSM/R/ExtKalmanFilter.R
PSM/R/PSM.simulate.R
PSM/R/APL.KF.R
PSM/R/invlogit.R
PSM/R/IndividualLL.KF.R
PSM/R/PSM.smooth.R
PSM/R/ExtKalmanSmoother.R
PSM/R/PSM.plot.R
PSM/R/APL.KF.gr.R
PSM/R/IndividualLL.KF.gr.R
PSM/R/matexp.R
PSM/R/LinKalmanSmoother.R
PSM/R/CutThirdDim.R
PSM/R/LinKalmanFilter.R
PSM/R/zzz.R
PSM/vignettes
PSM/vignettes/simisr.RData
PSM/vignettes/images
PSM/vignettes/images/comp2dose.eps
PSM/vignettes/images/isrmodel.pdf
PSM/vignettes/images/isrmodel.eps
PSM/vignettes/images/comp2dose.pdf
PSM/vignettes/simdose.RData
PSM/vignettes/PSM.Rnw
PSM/MD5
PSM/DESCRIPTION
PSM/man
PSM/man/PSM.smooth.Rd
PSM/man/matexp.Rd
PSM/man/PSM.template.Rd
PSM/man/PSM.estimate.Rd
PSM/man/PSM-internal.Rd
PSM/man/PSM.simulate.Rd
PSM/man/PSM-package.Rd
PSM/man/PSM.plot.Rd