Functions for fitting linear and nonlinear mixedeffects models using
stochastic differential equations (SDEs). The package allows for any multivariate
nonlinear timevariant model to be specified, and it also handles multidimensional
input, covariates, missing observations, and specification of dosage regimen.
The provided pipeline relies on the coupling of the FOCE algorithm and Kalman filtering
as outlined by Klim et al (2009,
Package details 


Author  Stig Bousgaard Mortensen, Soeren Klim, Robert Miller 
Date of publication  20180512 16:27:48 UTC 
Maintainer  Robert Miller <[email protected]> 
License  GPL (>= 2) 
Version  0.812 
URL  http://www.imm.dtu.dk/psm 
Package repository  View on CRAN 
Installation 
Install the latest version of this package by entering the following in R:

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