Design and Monitoring of Survival Trials Accounting for Complex Situations

cp | Conditional power given observed log hazard ratio |

cpboundary | The stopping boundary based on the conditional power criteria |

cpstop | The stopping probability based on the stopping boundary |

fourhr | A utility functon |

innercov | A utility function to calculate the inner integration of the... |

innervar | A utility function to calculate the inner integration of the... |

instudyfindt | calculate the timeline in study when some or all subjects... |

ovbeta | calculate the overall log hazard ratio |

overallcov | calculate the overall covariance |

overallcovp1 | calculate the first part of the overall covariance |

overallcovp2 | calculate the other parts of the overall covariance |

overallvar | calculate the overall variance |

pwe | Piecewise exponential distribution: hazard, cumulative... |

PWEALL2-package | Design and Monitoring of Survival Trials Accounting for... |

pwecx | Various function for piecewise exponential distribution with... |

pwecxcens | Integration of the density of piecewise exponential... |

pwecxpwu | Integration of the density of piecewise exponential... |

pwecxpwufindt | calculate the timeline when certain number of events... |

pwecxpwuforvar | calculate the utility function used for varaince calculation |

pwefv2 | A utility function |

pwefvplus | A utility functon |

pwepower | Calculating the powers of various the test statistics for... |

pwepowereq | Calculating the powers of various the test statistics for... |

pwepowerfindt | Calculating the timepoint where a certain power of the... |

pwepowerni | Calculating the powers of various the test statistics for... |

pwesim | simulating the test statistics |

pwu | Piecewise uniform distribution: distribution |

qpwe | Piecewise exponential distribution: quantile function |

qpwu | Piecewise uniform distribution: quantile function |

rmstcov | Calculation of the variance and covariance of estimated... |

rmsth | Estimate the restricted mean survival time (RMST) and its... |

rmstpower | Calculate powers at different cut-points based on difference... |

rmstpowerfindt | Calculating the timepoint where a certain power of mean... |

rmstsim | simulating the restricted mean survival times |

rmstutil | A utility function to calculate the true restricted mean... |

rpwe | Piecewise exponential distribution: random number generation |

rpwecx | Piecewise exponential distribution with crossover effect:... |

rpwu | Piecewise uniform distribution: random number generation |

spf | A utility function |

wlrcal | A utility function to calculate the weighted log-rank... |

wlrcom | A function to calculate the various weighted log-rank... |

wlrutil | A utility function to calculate some common functions in... |

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