rmsth: Estimate the restricted mean survival time (RMST) and its...

In PWEALL: Design and Monitoring of Survival Trials Accounting for Complex Situations

Estimate the restricted mean survival time (RMST) and its variance from data

Description

A function to estimate the restricted mean survival time (RMST) and its variance from data

Usage

rmsth(y=c(1,2,3),d=c(1,1,0),tcut=2.0,eps=1.0e-08)

Arguments

y	observed times
d	non-censoring indicators
tcut	time point at which rmst is calculated
eps	A small number representing the error tolerance when comparing the event times

Details

More details

Value

tcut	time point at which rmst is calculated
rmst	estimated RMST
var	estimated variance of rmst
vadd	estimated variance-covariance term of rmst

Note

This estimates the restricted mean survival time and its asymptotic variance

Author(s)

Xiaodong Luo

References

Luo, et al. (2017)

Examples

lamt<-0.8
lamc<-0.4
n<-3000
tcut<-2.0
truermst<-(1-exp(-lamt*tcut))/lamt
tt<-rexp(n)/lamt
cc<-rexp(n)/lamc
yy<-pmin(tt,cc)
dd<-rep(1,n)
dd[tt>cc]<-0
aest<-rmsth(y=yy,d=dd,tcut=tcut)
aest

PWEALL documentation built on Aug. 9, 2023, 9:08 a.m.