load_example_seurat: Example Seurat Object for PopComm Package

In PopComm: Population-Level Cell-Cell Communication Analysis Tools

Example Seurat Object for PopComm Package

Description

A preprocessed Seurat object containing single-cell RNA sequencing data for demonstration and testing purposes across functions in the PopComm package. The object includes normalized expression data, metadata with sample and cell type annotations, and basic preprocessing steps (e.g., dimensionality reduction).

Usage

load_example_seurat()

Format

A Seurat object with the following slots:

assays

RNA count matrix normalized by log1p.

meta.data

Dataframe containing metadata columns:

• sample: Sample identifier (e.g., "sample1", "sample2").

• broad.cell.type: Cell type annotations (e.g., "Cardiac", "Fibroblast").

reductions

PCA and UMAP embeddings for visualization.

Value

A Seurat object containing example single-cell RNA-seq data. If the download fails, the function returns NULL.

Source

Subset of snRNA-seq data analyzed in our study, processed via standard workflow (see manuscript for details). Full dataset available at Zenodo (DOI: 10.XXXX/zenodo.XXXXX).

PopComm documentation built on June 8, 2025, 1:45 p.m.