simu.VEGs: SCRIP simulation for clustering analysis

In SCRIP: An Accurate Simulator for Single-Cell RNA Sequencing Data

Description

Simulate count data for clustering analysis by preserving variably expressed genes

Usage

simu.VEGs(
  counts.matrix,
  params = params,
  base_allcellmeans,
  mode = "GP-trendedBCV",
  nCells,
  nfeatures = 1000
)

Arguments

counts.matrix	data matrix required for simulation
params	SplatParams object containing parameters for the simulation
base_allcellmeans	base cell means specified directly for simulating counts
mode	"GP-commonBCV", "BP-commonBCV", "BP", "BGP-commonBCV" and "BGP-trendedBCV"
nCells	number of cells simulated
nfeatures	parameter required for FinalVariable function in Seurat package

Value

simulated read counts data

SCRIP documentation built on Nov. 19, 2021, 9:07 a.m.