Description Usage Arguments Value Examples

This function generates synthetic from the fixed effects model described in the experimental studies portion of the paper.

1 2 3 4 5 6 7 8 9 10 11 12 13 | ```
makeSimData(
H,
n,
L = 100,
maf = 0.01,
gamma0 = 1,
gammaX = 1,
gammaE = 1,
gammaG,
gammaGE,
causal = 40,
seed = 12345
)
``` |

`H` |
Matrix of haplotype data (e.g. cosihap) |

`n` |
Number of individuals |

`L` |
Number of SNPs in the G matrix (Default is 100), should be a value between 1 and 604 |

`maf` |
Minor allele frequency (Default is 0.01) |

`gamma0` |
gamma0 Fixed effect coefficient for intercept (Default is 1) |

`gammaX` |
gammaX Fixed effect coefficient for confounding covariates (Default is 1) |

`gammaE` |
gammaE Fixed effect coefficient for E effect (Default is 1) |

`gammaG` |
gammaG Fixed effect coefficient for G main effect |

`gammaGE` |
gammaGE Fixed effect coefficient for GxE interaction effect |

`causal` |
Number of causal SNPs (default is 40) |

`seed` |
Seed (Default is 12345) |

Synthetic dataset containing y, X, E, G, epsilon, and number of causal SNPs

1 | ```
dat <- makeSimData(H=cosihap, n=500, L=10, gammaG=1, gammaGE=0, causal=4, seed=1)
``` |

Embedding an R snippet on your website

Add the following code to your website.

For more information on customizing the embed code, read Embedding Snippets.