SITH: A Spatial Model of Intra-Tumor Heterogeneity

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

Package details

AuthorPhillip B. Nicol
MaintainerPhillip B. Nicol <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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SITH documentation built on Jan. 5, 2021, 5:08 p.m.