SMARTbayesR: SMARTbayesR: A package for Bayesian computation of optimal...

Description SMARTbayesR functions

Description

The SMARTbayesR package allows computation of a set of optimal embedded dynamic treatment regimes for a SMART. Furthermore, it allows power to be calculated for sample size determination.

SMARTbayesR functions

SimDesign1 simulates a design-1 type SMART

PosteriorTrtSeqProb draws from the posterior of the probabilities of response for each embedded treatment sequence and stage-1 response probabilities.

PosteriorEDTRProbs converts treatment sequence end of study response probabilities, stage-1 response probabilities into end of study embedded dynamic treatment regime response probabilities.

MCBUpperLimits calculates simultaneous credible intervals which determines the set of optimal dynamic treatment regimes

LogOR computes the log-OR between each embedded dynamic treatment regime and the best.

LogRR computes the log-RR between each embedded dynamic treatment regime and the best.

RD computes the risk difference between each embedded dynamic treatment regime and the best.

PowerBayesian computes the power in a SMART to exclude embedded dynamic treatment regimes inferior to the best by a specified amount.

Please see Artman (2020) <arXiv:2008.02341> for details about the methodology.


SMARTbayesR documentation built on Oct. 1, 2021, 1:06 a.m.