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Computes the required sample size using the optimal designs with multiple constraints proposed in Mayo et al.(2010). This optimal method is designed for two-arm, randomized phase II clinical trials, and the required sample size can be optimized either using fixed or flexible randomization allocation ratios.
Package details |
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Author | Wei Jiang, Jonathan Mahnken, Matthew Mayo |
Maintainer | Wei Jiang<wjiang@kumc.edu> |
License | GPL-2 |
Version | 1.0 |
Package repository | View on CRAN |
Installation |
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