SimReg-package: Similarity Regression Functions
In SimReg: Similarity Regression
SimReg-package R Documentation
Similarity Regression Functions
Description
Functions for performing Bayesian similarity regression,
and evaluating the probability of association between sets of ontological terms
and binary response vector. A random model is compared with one in which
the log odds of a true response is linked to the semantic similarity
between terms and a latent characteristic ontological profile.
Details
Key functions include sim_reg, for similarity regression of binary response variable against an ontologically encoded predictor. An example application would be inferring the probability of association between the presence of a rare genetic variant conditional on an ontologically encoded phenotype.
Author(s)
Daniel Greene <dg333@cam.ac.uk>
Maintainer: Daniel Greene <dg333@cam.ac.uk>
References
D. Greene, NIHR BioResource, S. Richardson, E. Turro, ‘Phenotype similarity regression for identifying the genetic determinants of rare diseases’, The American Journal of Human Genetics 98, 1-10, March 3, 2016.
SimReg documentation built on May 29, 2024, 8:40 a.m.
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| SimReg-package | R Documentation |
Similarity Regression Functions
Description
Functions for performing Bayesian similarity regression, and evaluating the probability of association between sets of ontological terms and binary response vector. A random model is compared with one in which the log odds of a true response is linked to the semantic similarity between terms and a latent characteristic ontological profile.
Details
Key functions include sim_reg, for similarity regression of binary response variable against an ontologically encoded predictor. An example application would be inferring the probability of association between the presence of a rare genetic variant conditional on an ontologically encoded phenotype.
Author(s)
Daniel Greene <dg333@cam.ac.uk>
Maintainer: Daniel Greene <dg333@cam.ac.uk>
References
D. Greene, NIHR BioResource, S. Richardson, E. Turro, ‘Phenotype similarity regression for identifying the genetic determinants of rare diseases’, The American Journal of Human Genetics 98, 1-10, March 3, 2016.
R Package Documentation
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Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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