Man pages for SimTOST
Sample Size Estimation for Bio-Equivalence Trials Through Simulation
| check_equivalence | Check Equivalence for Multiple Endpoints |
| derive_allocation_rate | Derive and Validate Treatment Allocation Rate (TAR) |
| derive_arm_names | Derive or Assign Arm Names |
| derive_endpoint_names | Derive Endpoint Names |
| derive_varcov_list | Derive Variance-Covariance Matrix List |
| get_par | Parameter Configuration for Endpoints and Comparators |
| info_msg | Helper function for conditional messages |
| mcsapply | mcsapply |
| plot.simss | Plot Power vs Sample Size for Simulation Results |
| power_cal | Calculate the power across all comparators |
| power_dom | Power Calculation for Difference of Means (DOM) Hypothesis... |
| power_Mielke | Power Calculation for Hypothesis Testing in Equivalence... |
| print.simss | Print Summary of Sample Size Estimation |
| ptv | Compute p-values for a t-distribution with Fixed Degrees of... |
| ptvdf | Calculate p-values using t-distribution with Variable Degrees... |
| run_simulations_2x2_dom | Run Simulations for a 2x2 Crossover Design with Difference of... |
| run_simulations_2x2_rom | Run Simulations for a 2x2 Crossover Design with Ratio of... |
| run_simulations_par_dom | Run Simulations for a Parallel Design with Difference of... |
| run_simulations_par_rom | Run Simulations for a Parallel Design with Ratio of Means... |
| sampleSize | Sample Size Calculation for Bioequivalence and Multi-Endpoint... |
| sampleSize_Mielke | Sample Size Estimation for Multiple Hypothesis Testing Using... |
| sign_Mielke | Simulated Test Statistic for Noninferiority/Equivalence... |
| simParallelEndpoints | Generate Simulated Endpoint Data for Parallel Group Design |
| SimTOST | Sample Size Estimation via Simulation |
| test_2x2_dom | Simulate a 2x2 Crossover Design and Compute Difference of... |
| test_2x2_rom | Simulate a 2x2 Crossover Design and Compute Ratio of Means... |
| test_par_dom | Simulate a Parallel Design and Test Difference of Means (DOM) |
| test_par_rom | Simulate a Parallel Design and Test Ratio of Means (ROM) |
| test_studies | test_studies |
| uniroot.integer.mod | Optimizer for Uniroot Integer (Modified) |
| validate_positive_definite | Validate Positive Semi-Definite Matrices |
| validate_sample_size_limits | Check Sample Size Limits |
