SurrogateOutcome: Estimation of the Proportion of Treatment Effect Explained by Surrogate Outcome Information

Provides functions to estimate the proportion of treatment effect on a censored primary outcome that is explained by the treatment effect on a censored surrogate outcome/event. All methods are described in detail in "Assessing the Value of a Censored Surrogate Outcome" by Parast L, Tian L, and Cai T which is currently in press at Lifetime Data Analysis. The main functions are (1) R.q.event() which calculates the proportion of the treatment effect (the difference in restricted mean survival time at time t) explained by surrogate outcome information observed up to a selected landmark time, (2) R.t.estimate() which calculates the proportion of the treatment effect explained by primary outcome information only observed up to a selected landmark time, and (3) IV.event() which calculates the incremental value of the surrogate outcome information.

Package details

AuthorLayla Parast
MaintainerLayla Parast <[email protected]>
LicenseGPL
Version1.0
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("SurrogateOutcome")

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SurrogateOutcome documentation built on May 1, 2019, 9:25 p.m.